Nanoparticle PEGylation for Cancer Therapy
نویسندگان
چکیده
منابع مشابه
Nanoparticle PEGylation for Cancer Therapy
Currently, there are more than 35 US FDA-approved NPs utilizing PEG in their biomedical applications. PEGylation, which is the addition of PEG to the NP formulation, provides immunity from the hostile biological environment. The ‘stealth’ property, further confers on the PEG-NP formulation benefits that are not normally provided by other polymers. This mini-review briefly describes the mechanis...
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Nanoparticles are an essential component in the emerging field of nanomedical imaging and therapy. When deployed in vivo, these materials are typically protected from the immune system by polyethylene glycol (PEG). A wide variety of strategies to coat and characterize nanoparticles with PEG has established important trends on PEG size, shape, density, loading level, molecular weight, charge and...
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BACKGROUND Theranostic nanomaterials composed of fluorescent and photothermal agents can both image and provide a method of disease treatment in clinical oncology. For in vivo use, the near-infrared (NIR) window has been the focus of the majority of studies, because of greater light penetration due to lower absorption and scatter of biological components. Therefore, having both fluorescent and ...
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ژورنال
عنوان ژورنال: MOJ Proteomics & Bioinformatics
سال: 2015
ISSN: 2374-6920
DOI: 10.15406/mojpb.2015.02.00037